Indian Dermatology Online Journal

REVIEW ARTICLE
Year
: 2021  |  Volume : 12  |  Issue : 7  |  Page : 12--23

Preparation of platelet-rich plasma: National IADVL PRP taskforce recommendations


Shuken Dashore1, Kavish Chouhan2, Soni Nanda3, Aseem Sharma4 
1 Dr Dashore's DHL Centre, Vijay Nagar, Indore, Madhya Pradesh, India
2 Consultant Dermatologist and Hair Transplant Surgeon, DERMACLINIX, E13 Defence Colony, Delhi, India
3 Consultant Dermatologist, Shine and Smile Clinic, Mayur Vihar, Delhi, India
4 Dermatology Department, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Shuken Dashore
Dr Dashore's DHL Centre, Vijay Nagar, Indore - 452 010, Madhya Pradesh
India

The goal of these recommendations is to provide a framework to practitioners for implementing useful, evidence-based recommendations for the preparation of platelet-rich plasma (PRP) in various dermatological indications. The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) assigned the task of preparing these recommendations to its task force on PRP. A comprehensive literature search was done in the English language on the preparation of PRP across multiple databases. The grade of evidence and strength of recommendation was evaluated on the GRADE framework (Grading of Recommendation, Assessment, Development and Evaluation). A draft of clinical recommendations was developed on the best available evidence which was also scrutinized and critically evaluated by the IADVL Academy of Dermatology. Based on the inputs received, this final consensus statement was prepared. A total of 45 articles (meta-analyses, prospective and retrospective studies, reviews [including chapters in books], and case series) were critically evaluated and the evidence thus gathered was used in the preparation of these recommendations. This expert group recommends the use of double-spin manual method for the preparation of PRP. The recommended parameters for centrifuge are 100–300 g for 5–10 min for the first spin and 400–700 g for 10–17 min for the second spin. The recommended platelet concentration in PRP for the treatment of various dermatological conditions is 1–1.5 million platelets/μL. The activation of PRP is not required when it is injected into soft tissues.


How to cite this article:
Dashore S, Chouhan K, Nanda S, Sharma A. Preparation of platelet-rich plasma: National IADVL PRP taskforce recommendations.Indian Dermatol Online J 2021;12:12-23


How to cite this URL:
Dashore S, Chouhan K, Nanda S, Sharma A. Preparation of platelet-rich plasma: National IADVL PRP taskforce recommendations. Indian Dermatol Online J [serial online] 2021 [cited 2022 Jan 24 ];12:12-23
Available from: https://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=7;spage=12;epage=23;aulast=Dashore;type=0