• Users Online: 688
  • Print this page
  • Email this page
SYMPOSIUM ARTICLE: IADVL PRP TASKFORCE (IADVL ACADEMY)
Year : 2021  |  Volume : 12  |  Issue : 7  |  Page : 31-40

Platelet-rich plasma in androgenetic alopecia


1 Chief Dermatologist, Skin Saga Centre for Dermatology, Mumbai, Maharashtra, India
2 Director and Consultant Dermatologist, DERMACLINIX, New Delhi, India
3 Director and Consultant Dermatologist, DERMETICS, Mumbai, Maharashtra, India
4 Consultant Dermatologist, DHL Skin Centre, Indore, Madhya Pradesh, India

Correspondence Address:
Dr. Aseem Sharma
Chief Dermatologist, Skin Saga Centre for Dermatology, Andheri West - 400 053, Mumbai, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/idoj.idoj_328_21

Rights and Permissions

The goal of these recommendations is to provide a framework to practitioners for implementing useful, evidence-based recommendations for the preparation of platelet-rich plasma (PRP) and its use in androgenetic alopecia (AGA). The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) assigned the task of preparing these recommendations to its taskforce on PRP. A comprehensive literature search was done in the English language on the PRP across multiple databases. The grade of evidence and strength of recommendation were evaluated on the GRADE (Grading of Recommendation, Assessment, Development, and Evaluation) framework. A draft of clinical recommendations was developed on the best available evidence, which was also scrutinized and critically evaluated by the IADVL Academy of Dermatology. Based on the inputs received, the final consensus statement was prepared. A total of 30 articles (meta-analyses, prospective and retrospective studies, reviews [including chapters in books], and case series) were critically evaluated, and the evidence thus gathered was used in the preparation of these recommendations. This expert group recommends use of manual double-spin method for the preparation of PRP for AGA. Minimum three to five sessions of PRP are recommended for AGA with a gap of 1 month between the two sessions. Patients with Grade II to V Norwood Hamilton classification of AGA are the ideal subset for PRP. A total of 5 to 7 mL of PRP and 0.05 to 0.1 mL/cm2 is the recommended dose of PRP for AGA. Activation of PRP is not required when it is used for AGA. About 1 to 1.5 million platelets/μL of platelets in PRP is the recommended platelet concentration in PRP for the treatment of AGA. I-PRF (injectable platelet-rich fibrin) has also been found to be useful in AGA, although further studies are required to establish its role. PRP can also have an adjunctive role in hair transplantation procedures.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed393    
    Printed0    
    Emailed0    
    PDF Downloaded94    
    Comments [Add]    

Recommend this journal