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Year : 2012  |  Volume : 3  |  Issue : 2  |  Page : 157-158  

Vulval Syringoma: First report of a case in an Egyptian female

Department of Dermatology, Al Minya University Hospital, Al Minya, Egypt

Date of Web Publication29-May-2012

Correspondence Address:
Eman S Abdel-Azim
Department of Dermatology, Al Minya University Hospital, Al Minya
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5178.96731

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How to cite this article:
El-Domyati MM, Abdel-Raouf HM, El-Ammawi T, Abdel-Azim ES. Vulval Syringoma: First report of a case in an Egyptian female. Indian Dermatol Online J 2012;3:157-8

How to cite this URL:
El-Domyati MM, Abdel-Raouf HM, El-Ammawi T, Abdel-Azim ES. Vulval Syringoma: First report of a case in an Egyptian female. Indian Dermatol Online J [serial online] 2012 [cited 2022 Jan 18];3:157-8. Available from: https://www.idoj.in/text.asp?2012/3/2/157/96731

A 23-year-old married woman presented with a history of multiple, pinhead-sized vulval skin lesions since nine months. The patient noticed no exacerbation of the lesions during menstruation or summer season. There was no history of similar lesions elsewhere or in among the family members. She denied any extramarital relationships. She had been treated with topical steroid preparations in the past without any relief. Serology for VDRL and HIV was negative. Abdominal ultrasonography revealed no organomegaly.

On examination, there were multiple, discrete, bilateral and symmetrical soft skin-colored papules with smooth surface measuring 2-5 mm in diameter present over the labia majora [Figure 1]a and b.
Figure 1: a,b: Skin colored bilaterally symmetrical papules over the vulva

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Per speculum examination revealed no similar vaginal or cervical lesions. Systemic examination was normal. A clinical differential diagnosis of syringomas, Fox-Fordyce's disease, milia, epidermal cysts, steatocystoma multiplex and genital warts was considered.

Histopathology of one of the lesions revealed numerous cystic ducts lined by two rows of epithelial cells embedded in a fibrocollagenus stroma [Figure 2]a. Lumen of the ducts contained amorphous debris. Some of the ducts showed small comma like tails of epithelial cells (tadpole appearance) in the papillary and reticular dermis [Figure 2]b. These observations were consistent with the clinical diagnosis of syringoma.
Figure 2: a: Numerous cystic ducts lined by two rows of epithelial cells embedded in a fi brocollagenous stroma (H and E, ×20)
Figure 2: b: Lumen of ducts containing amorphous debris. Some of the ducts show small comma-like tails of epithelial cells (tadpole appearance) (H and E, ×40)

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Syringoma is a benign neoplasm that arises from the intraepidermal eccrine sweat duct. Its name was derived from the Greek word syrinx, which means pipe or tube. [1] Syringoma was first described in 1872 by Kaposi and Biesiadeki as lymphangioma tuberosum multiplex. [2] The prevalence of this tumor may be greater than previously reported due to the fact that many are asymptomatic and are unrecognized by both patients and clinicians. Vulvar syringomas (VS) have commonly been described in association with extragenital lesions. [3] Our case showed only vulval lesions with clinical and histological features of syringoma.

The main reason for treatment is cosmetic disfigurement, the treatment options being dermabrasion, cryotherapy, electro-cauterisation, CO 2 laser and full-thickness grafting. [4]

The aim of reporting this case is to highlight a rare genital lesion which, though benign, is embarrassing to the patient. VS are under reported as they may not be recognized over the genitalia in case they are asymptomatic. VS must be considered in the differential diagnosis of all papular lesions over the vulva.

   References Top

1.Miranda JJ, Shahabi S, Salih S, Bahtiyar OM. Vulval syringoma: Report of a case and review of the literature. Yale J Bio Med 2002;75:207-10.  Back to cited text no. 1
2.Kaposi M. Hebra diseases of the skin. Vol. 3. Lymphangioma Tuberosum Multiplex. London: The New Sydendham Society; 1874. p. 386.  Back to cited text no. 2
3.Young AW, Herman EW, Tovell HM. Syringoma of the vulva: Incidence, diagnosis and cause of pruritus. Obstet Gynecol 1980;55:515-8.  Back to cited text no. 3
4.Karam P, Benedetto AD. Syringomas: New approach to an old technique. Int J Dermatol 1996;35:219-20.  Back to cited text no. 4


  [Figure 1], [Figure 2]

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